I'm not good with layouts. So when my client requested I make one just like the image he provided, I was sorta worried. I tinkered away for awhile and with some help from Twitter's bootstrap and I think I did a good job.
As a skeleton possibly. Really for a site like this I would keep it blue and black, a very clean and flat style.
Don't use gradients, just keep in nice and clean for that type of style. I think it would work quite well with this type of project. The use of simple 1px black and white lines can be very useful as well.